Saynisyahanka maamulaha MingCeler

Dr. Guangming Wu, PhD

Dr. Guangming Wu, oo ah borofisar ka tirsan Shaybaadhka Guangzhou Bio-land, wuxuu u shaqeeyay sidii la-hawlgal cilmi-baaris ama cilmi-baaris ka dib Xarunta Xayawaanka Caafimaadka ee New England, Jaamacadda Brown, Jaamacadda Missouri-Columbia, Jaamacadda Macbadka ee Caafimaadka, iyo machadyo kale oo caalami ah oo cilmi-baaris ah. .2004, wuxuu ku biiray Max Planck Institute for Molecular Biology (MPI) ee Jarmalka, halkaas oo uu kala shaqeeyay Prof. Hans R. Schöler (Xubin ka tirsan Akadeemiyada Qaranka ee Sayniska Jarmalka) horumarinta embriyaha jiirka iyo hababka unugyada stem.

Dr. Wu waxa uu ka shaqaynayay hababka molecular ee bini'aadamka, doofaarka, lo'da, iyo mouse oocyte iyo horumarinta uurjiifka hore, iyo samaynta totipotency iyo pluripotency in ka badan 30 sano, wuxuuna si fiican u yaqaanaa embriyaha kala duwan ee dhaqanka vitro iyo micro micro farsamooyinka wax-is-daba-marinta.Isagu waa saynisyahanka ugu horreeya iyo hadda kaliya ee kordhiya heerka dhalashada jiirarka laga helay tignoolajiyada magdhowga tetraploid min 1-5% ilaa 30-60% iyada oo loo marayo wanaajinta, gaaritaanka warshadaynta tignoolajiyada.Waxa uu si wadajir ah u qoray 79 waraaqaha SCI oo leh saameyn isku dhafan oo ka badan 670 iyo in ka badan 7150 xigasho wuxuuna ku daabacay joornaalada caalamiga ah ee ugu sarreeya sida Nature, Cell stem cell, iwm.

Waxtarka muuqda ee uu ka geystay wax-is-daba-marinta embriyaha, magaca Dr. Wu waxa uu si joogto ah uga dhex muuqdaa Matxafka Deutsches ee Munich, kaas oo ah matxafka sayniska iyo tignoolajiyada ugu weyn adduunka.

Bishii Agoosto 2019, Dr. Wu waxaa dib loogu soo celiyay Shiinaha isagoo ah cilmi-baare waqti-buuxa ah, isaga iyo kooxdiisa cilmi-baarista waxay si guul leh u dhiseen qaabka jiirka bani-aadamka ee ACE2 35 maalmood gudahood, iyagoo dhigay tijaabo "aasaas" tijaabo ah oo loogu talagalay cilmi-baarista COVID-19 pathogenesis. baaritaanka daroogada, iyo horumarinta tallaalka.Guulihiisa quruxda badan ee sayniska iyo tignoolajiyada awgeed, Dr. Wu waxa la guddoonsiiyay "Shakhsi Sare oo La Dagaallanka COVID-19 ee Gobolka Guangdong" 2020.

Horumarka guusha leh iyo adeegsiga jiilka soo socda ee Tetraploid Complementation technology (TurboMice™ technology) ee mouse modeling inta lagu guda jiro dagaalka ka dhanka ah COVID-19, ku dhiiri Dr. Wu inuu ku dadaalo qiimo weyn ee horumarinta biopharmaceuticals.Sidaa darteed, wuxuu la wadaagay Guangzhou MingCeler Biotech Co., Ltd oo ah saynisyahan maamule, isaga oo ka go'an isbeddelka tignoolajiyada TurboMice ™ ee shaybaarka ilaa codsiyada warshadaha si ay u bixiso nooc-dhamaadka sare ee badeecadaha iyo adeegyada jiirarka adduunka, machadyada cilmi-baarista, isbitaallada, iyo shirkadaha dawooyinka ee ku lug leh cilmi-baarista caafimaadka nolosha.